Comparison between the effect of oral Melatonin and Hydroxyzine for Preventing Preoperative Anxiety in pediatric Patients Undergoing Adenotonsillectomy
The aim of the study is to compare the effectiveness of preoperative oral melatonin and hydroxyzine on preoperative anxiety in pediatric patients undergoing adenotonsillectomy. The primary outcomes: 1. Ease of parenteral separation. 2. The compliance to anesthesia induction in pediatric patients. The secondary outcomes: 1. Assessment of postoperative pain. 2. Time to first analgesic request.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
78
0.1 mg/ kg melatonin in 10 ml apple juice 1 hour before induction of anesthesia
1 mg/ kg hydroxyzine in 10 ml apple juice 1 hour before induction of anesthesia
10 ml apple juice 1 hour before induction of anesthesia
Sarah Omar
Al Minyā, Egypt
RECRUITINGEase of parenteral separation.
Recorded as excellent, good, fair, or poor when the child is separated from the parent
Time frame: 20-30 minutes after administration
The compliance to anesthesia induction in pediatric patients.
Assessed by a modified Yale preoperative anxiety scale, the range is from 5 to 22, the lower score is better
Time frame: one hour after administration
Assessment of postoperative pain
Face, Leg, Activity, Cry, and Consolability (FLACC) Scale from 0 to 10, the lower score is better
Time frame: immediately before and at induction procedure
First analgesic request
Paracetamol
Time frame: Three hours postoperative
Hanafy
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