Efficacy and Safety of Products Containing Marine Collagen Peptide and Coenzyme Q10 for Skin Rejuvenation

USMARI Research & Innovation Centre32 enrolled

Overview

This is a placebo-controlled study conducted to investigates the safety and efficacy of products containing marine collagen peptide and CoQ10 in enhancing skin rejuvenation of Malaysian women. The study duration is 28 days and the skin assessment will be carried out at baseline, Day 14 and Day 28.The main questions it aims to answer are: 1. The effect of product on skin hydration of women in Malaysia. 2. The effect of product on skin elasticity of women in Malaysia. 3. The effect of product on skin wrinkle of women in Malaysia. 4. The skin brightening effect of product on Malaysian women. 5. To observe any adverse effect occurrence with the consumption of the product.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

OTHER

Masking

SINGLE

Enrollment

Conditions

Healthy

Interventions

Eligibility

Sex: FEMALEMin age: 35 YearsMax age: 45 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Malaysian citizen * Women aged 35 - 45 years old * Willing to participate Exclusion Criteria: * Women with skin diseases or any underlying diseases. * Pregnant, breastfeeding women or planned pregnancy during the study period * Allergy to collagen or other ingredients that may be found in the product. * Women who had any cosmetic procedures such as botox, laser and light treatment, facial surgery, and any procedures that may improve skin hydration, elasticity, wrinkles, and brightening of skin four weeks before the study. * Women who took any dietary supplements, functional foods, or medicines that could have the same or similar effects as the product evaluated in this study in the past three months.

Outcomes

Primary Outcomes

Changes in skin hydration from baseline and at Day 14 and Day 28 after consumption of a product.

Skin hydration will be assessed using JANUS III skin analyzer and comparison will be made with placebo group.

Time frame: Baseline, Day 14 and Day 28

Changes in skin elasticity from baseline and at Day 14 and Day 28 after consumption of a product.

Skin elasticity will be assessed using JANUS III skin analyzer comparison will be made with placebo group.

Time frame: Baseline, Day 14 and Day 28

Changes in skin wrinkles from baseline and at Day 14 and Day 28 after consumption of a product.

Skin wrinkles will be assessed using JANUS III skin analyzer comparison will be made with placebo group.

Time frame: Baseline, Day 14 and Day 28

Changes in skin tone from baseline and at Day 14 and Day 28 after consumption of a product.

Skin hydration will be assessed using JANUS III skin analyzer comparison will be made with placebo group.

Time frame: Baseline, Day 14 and Day 28

Adverse effect after consumption of product containing marine collagen peptide and coenzyme Q10.

Based on adverse effect occurrence on participants that occur during study period (28 days)

Time frame: 28 Days

Efficacy and Safety of Products Containing Marine Collagen Peptide and Coenzyme Q10 for Skin Rejuvenation

Overview

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Primary Outcomes