Bioavailability and Bioequivalence of Ezetimibe Tablets in Healthy Subjects

Inclusion Criteria: * Healthy male or female subjects ≥18 years of age * The body mass index is in the range of 18.0-26.0 kg/m2 (including the critical value). * The weight of male is not less than 50.0 kg, and that of female is not less than 45.0 kg. * Serum total cholesterol was between 2.9 and 5.0mmol/L (not including critical value). Exclusion Criteria: * any medical history of cardiovascular, digestive, respiratory, nervous or ematological diseases * hepatic/renal impairment * abnormal vital signs * drug or alcohol abuse * smoking ≥5 cigarettes per day , * donation(≥300ml) o * enrollment in other clinical trials during the 3 months prior to screening * allergic to ezetimibe or its excipients * any use of other prescription drugs or vitamins or caffeine/xanthine-rich beverages 48h prior to taking medication * lactating or pregnant women