Plaque Burden and Ischemia in MINOCA

University of Bergen100 enrolled

Overview

The goal of this clinical trial is to assess coronary artery plaque burden, perivascular inflammation and extent of myocardial ischemia in patients presenting with acute myocardial infarction and non-obstructive coronary artery disease. The main question it aims to answer are: * Identify coronary artery anatomy, plaque burden, composition and high-risk plaque features by CT coronary angiography in MINOCA * Assess presence, extent and severity of myocardial ischemia in MINOCA Participants will examined by CT coronary angiography and stress \[12N\] NH3 PET-MR.

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

MINOCA

Interventions

CT coronary angiography and [12N] NH3 PET-MRDIAGNOSTIC_TEST

Advanced coronary artery plaque analysis, myocardial ischemia and coronary flow reserve

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Acute chest pain * Elevated troponin * Non-obstructive coronary arteries by coronary angiography Exclusion Criteria: * Obstructive coronary artery disease * Contraindications against CT coronary angiography or stress \[12N\] NH3 PET-MR * Not able to give informed consent

Locations (1)

Department of Clinical Science, University of Bergen

Bergen, Norway

RECRUITING

Outcomes

Primary Outcomes

Plaque burden

Time frame: 1 week

Myocardial ischemia

Time frame: 1 week

Data from ClinicalTrials.gov

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