Immunoglobulin G4 and Immunoglobulin E Antibodies in a Population With Adverse Reactions to Foodstuffs-related Symptoms

N/ARecruitingNCT05681975

Universidad Politecnica de Madrid200 enrolled

Overview

The aim of this study is to analyze a population with symptoms associated with adverse reactions to foodstuffs (ARFS). To determine the levels of food-specific immunoglobulin G4 (IgG4) and immunoglobulin E (IgE) antibody reactions (AbR).

Volunteers with symptoms related with adverse reactions to foodstuffs (ARFS) and suspicion of having a food allergy or a food intolerance are enrolled in this study. A 50μl of capillary whole blood is analyzed and the levels of food-specific immunoglobulin G4 (IgG4) or immunoglobulin E (IgE) antibody reactions (AbR) are determined.

Study Type

OBSERVATIONAL

Enrollment

200

Conditions

Immunoglobulin E-Mediated Food Allergy Immunoglobulin G4-Related Disease Symptoms and Signs Adverse Reaction to Food

Interventions

Immunoassay kits (NutriSMART® and Fastcheckpoc20® In-Vitro Diagnostic kits, DST GmbH, Schwerin, Germany) are performed in a population with suspicion of having a food allergy or a food intolerance with related symptoms.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Adults (\>18 years of age) * To present symptoms related to adverse reactions to foodstuffs (ARFS) Exclusion Criteria: * Antibiotic treatment

Outcomes

Primary Outcomes

Food-specific Immunoglobulin G4 antibody reactions

Immunoassay kits (NutriSMART® In-Vitro Diagnostic kit, DST GmbH, Schwerin, Germany) are performed in a population with suspicion of having a food allergy or a food intolerance with related symptoms.

Time frame: 0 days

Secondary Outcomes

Food-specific Immunoglobulin E antibody reactions

Immunoassay kits (Fastcheckpoc20® In-Vitro Diagnostic kit, DST GmbH, Schwerin, Germany) are performed in a population with suspicion of having a food allergy or a food intolerance with related symptoms.