Adjunctive Use Of A Novel Hyaluronic Acid/Chlorhexidine Gel In The Non Surgical Treatment Of Periodontitis

University of Sharjah20 enrolled

Overview

General Objective : To evaluate the outcome of non surgical periodontal therapy with local drug delivery adjunct to scaling and root planning Specific Objective : To determine the effect of intra-pocket application of hyaluronic acid /chlorohexidine gel in non surgical periodontal treatment on clinical periodontal parameters and microbiological level .

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Periodontitis Hyaluronic Acid Chlorhexidine

Interventions

Non surgical periodontal therapyPROCEDURE

Subgingival ultrasonic debridement + manual root planning

Eligibility

Sex: ALLMin age: 20 YearsMax age: 60 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Age : 20-60 years old * At least 20 remaining teeth * Periodontitis stage III and IV ,Grade A, B and C Exclusion Criteria: * Patients taking specific medications: antibiotic , anticoagulants or anti-inflammatory * Previous periodontal therapy in the past 3-6 months. * Immunocompromised patients * Systemically diseased patients: Diabetes ,osteoporosis etc * History of allergies or hypersensitivity reactions to chlorohexidine or Hyaluronic acid * Pregnant or lactating women. * Heavy Smokers (more than 20/day)

Locations (1)

University Dental Hospital Sharjah

Sharjah city, United Arab Emirates

RECRUITING

Outcomes

Primary Outcomes

pocket depth

Time frame: 2 months

Bleeding on Probing

Time frame: 2 months

Clinical attachment level

Time frame: 2 months

Secondary Outcomes

Plaque index

Time frame: 2 months

Central Contacts

Prof. Zahi Badran Prof.

CONTACT

+97165057353 zbadran@sharjah.ac.ae

Data from ClinicalTrials.gov

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