Alveolar Ridge Preservation With Layered Collagen and Xenograft

Ain Shams University20 enrolled

Overview

alveolar ridge preservation using deep collagen layer, xenograft and collagen membrane seal versus the use of xenograft and collagen membrane seal alone. Measuring the clinical and radiographic alveolar ridge dimensional changes following after preservation at the time of implant placement

alveolar ridge preservation using deep collagen layer, xenograft and collagen membrane seal versus the use of xenograft and collagen membrane seal alone. The primary objective of the study is measuring the clinical and radiographic alveolar ridge dimensional changes following the procedure 4 months post operatively The secondary objective : * Histological assessment of alveolar bone specimens to assess bone remodeling and new bone formation in both studied groups after four months. * Patient satisfaction after implant placement

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Alveolar Ridge Preservation

Interventions

deep collagen layer, xenograft and collagen membranePROCEDURE

Alveolar ridge preservation is done using deep collagen layer, xenograft and collagen membrane

xenograft and collagen membranePROCEDURE

Alveolar ridge preservation is done using xenograft and collagen membrane only

Eligibility

Sex: ALLMin age: 20 YearsMax age: 45 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Systemically healthy patients (American Society of Anesthesiologists I; ASA I). * Patients diagnosed with single unrestorable molar teeth (socket type I) requiring extraction and implant placement (Elian et al.2007). * Teeth free from any infection or periapical pathosis. * Enough zone of keratinized tissue with at least 2mm. * Good compliance with the plaque control instructions following initial therapy. * Availability for follow up and maintenance program. Exclusion Criteria: * Bad oral hygiene. * Presence of smoking habit. * Presence of occlusal interferences * Pregnant females * Vulnerable group of patients (handicapped, mentally retarded and prisoners) (according to the recommendation of esthetical committee of Faculty of Dentistry Ain Shams University).

Locations (1)

Faculty of Dentistry Ain Shams University

Cairo, Cairo Governorate, Egypt

Outcomes

Primary Outcomes

Measuring the clinical alveolar ridge changes

Measuring the thickness of the alveolar ridge in mm

Time frame: at baseline and 4 months

Measuring the radiographic change in the buccal bone thickness

Measuring the change in the thickness of the buccal ridge radiographically in mm

Time frame: at baseline and 4 months

Measuring the radiographic alveolar ridge dimensional changes

Measuring the bone density in hounsfield units (HU)

Time frame: at baseline and 4 months

Secondary Outcomes

Histological assessment of core biopsy

The microscopic examination of the bone remodeling and new bone through tissue biopsy (fixation and staining of the tissues) to examine the newly formed cells and count them to determine the amount of newly tissue formed

Time frame: 4 months post operatively

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.