Coronavirus Infection (COVID-19) and Radical Surgery in Patients With Early-stage Lung Cancer

N/AActive Not RecruitingNCT05684549

Ruijin Hospital2,000 enrolled

Overview

The goal of this observational study is to learn about the effects of coronavirus infection in patients with early-stage lung cancer. The main question it aims to answer is whether the interval of surgery and COVID-19 infection will affect the surgery and prognosis of the patients.

Study Type

OBSERVATIONAL

Enrollment

2,000

Conditions

Surgery Corona Virus Infection

Interventions

No interventionOTHER

Observational study, no intervention

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Clinically diagnosed stage I and stage II lung cancer, who are about to receive wedge resection, segmental resection, sleeve resection, lobectomy, or pneumonectomy under general anaesthesia. * Volunteer to participate in the study with good compliance. Able to complete the observation and follow-up and have signed the informed consent. * ASA score: I-III; * Cardiopulmonary functions meet the requirements of radical operation for lung cancer with normal liver and kidney functions. Exclusion Criteria: * Neurologic, mental illness or mental disorder which is hard to control, poor compliance, unable to cooperate or describe the treatment response; * Clinically diagnosed stage III and stage IV lung cancer or patients who received neoadjuvant treatment before surgery; * Patients developed symptoms alike coronavirus infection but are not confirmed by viral RNA detection by quantitative RT-PCR or antigen testing kits. * Serious heart, lung, liver and kidney dysfunction and unable to tolerate the operation

Locations (1)

Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

Shanghai, Shanghai Municipality, China

Outcomes

Primary Outcomes

postoperative morbidity

rate of perioperative complications, mainly include: pneumonia, respiratory failure, pulmonary embolism, arrhythmia, sepsis, cerebrovascular accident, myocardial injury, acute kidney injury.