This study will examine and record the patient's medical information and medical records (patient files, computer records, etc.). Physical examination, echocardiographic, electrocardiographic, laboratory, radiological, etc. evaluations are made during the routine controls of the patients. Within the scope of this study, no attempt will be made on the patients, no additional tests will be performed, or treatment changes will not be made in the patients because they are included in this study. After these records, KPET will be performed by a specialist doctor and physiotherapist for the patients who are directed to the Faculty of Physical Therapy and Rehabilitation Cardiopulmonary Rehabilitation Unit. Pulmonary function tests and respiratory muscle strength measurements will be performed on patients who have adequate rest after CPET.
Study Type
OBSERVATIONAL
Enrollment
78
CPET, the gold standard, will be used in the assessment of cardiorespiratory fitness. The cardiopulmonary exercise test system (Cosmed Quark CPET, Rome, Italy) is a safe method in which the patient can be monitored via ECG during the execution of the individual on a treadmill, and simultaneously lactate measurement, maximal O2 consumption, and CO2 production are evaluated. The Bruce protocol is the most commonly used method for KPET applied with a treadmill. However, since the Bruce protocol prefers high workload preferences, the Modified Bruce/half Bruce protocol with intermediate increments will be used. In addition, dyspnea, leg fatigue, and general fatigue at rest, during the test, and during the recovery phases after the test will be recorded with a sphygmomanometer using the Modified Borg Scale.
Pulmonary function testing will be performed with a spirometer (Cosmed Quark CPET, Rome, Italy) connected to the CPET system using standard procedures. Forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), FEV1/FVC, peak expiratory volume measured at 25% and 75% of forced expiratory time (FEF 25-75%), and peak expiratory volume (PEF) parameters will be saved.
Intraoral maximum inspiratory pressure (MIP) and maximum expiratory pressure (MEP) will be used as indicators of respiratory muscle strength. A portable intraoral pressure gauge (MicroRPM, Micromedical, Kent, UK) and nose clip will be used during MIP and MEP assessments. MIP and MEP measurements will be obtained using standard procedures. 3 measurements will be made where the difference between each measurement is not more than 10% and the maximum value of MIP and MEP will be recorded.
Hacettepe Unıversity
Ankara, Turkey (Türkiye)
RECRUITINGMaximal oxygen consumption
Time frame: 30-45 minutes
Forced vital capacity (FVC)
Time frame: 15-20 minutes
Forced expiratory volume in 1 second (FEV1)
Time frame: 15-20 minutes
FEV1/FVC
Time frame: 15-20 minutes
Maximal inspiratory pressure
Time frame: 15-20 minutes
Maximal expiratory pressure
Time frame: 15-20 minutes
Ratio curve of minute ventilation to carbon dioxide production (VE/VCO2) slope
Time frame: 30-45 minutes
Ratio of minute ventilation to carbon dioxide production (VE/VCO2)
Time frame: 30-45 minutes
Oxygen uptake efficiency slope (OUES)
Time frame: 30-45 minutes
Minute ventilation (VE)
Time frame: 30-45 minutes
End tidal oxygen pressure (PetO2)
Time frame: 30-45 minutes
End tidal carbon dioxide pressure (PetCO2)
Time frame: 30-45 minutes
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