Pain is one of the most prevalent symptoms during and after cancer. Pain can be the consequence of several situations (disease progression, surgery, and anticancer drugs). However, pain can frequently be associated with a substance use disorder (alcohol, tobacco, drugs, and illicit products such as cannabis). The relationship between substance use and pain is known to be complex and interdependent, i.e. pain can reinforce substance use and substance use can promote pain. However, few data in the literature are available on the use of psychoactive substances in relation to pain in the context of cancer (cancer patients and cancer survivors). Moreover, the scientific literature agrees on the fact that these elements are little studied and underestimated in the clinic. The investigators hypothesize that, in cancer patients or cancer survivors, the prevalence of the use of psychoactive substances would be higher in the presence of pain, and would be associated with its intensity and its impact on the quality Health-Related Living (HRQoL). The main objective of this study will be to compare, in an adult population of patients suffering from cancer or having had cancer, the prevalence of the consumption of psychoactive substances in painful patients compared to non-painful patients.
Patients will answer to an online questionnaire thanks to associations of cancer patients and social networks, in order to explore their substance use and pain status.
Study Type
OBSERVATIONAL
Enrollment
2,010
Online self-administered questionnaire exploring substance use, pain, chemotherapy-induced peripheral neuropathy, health-related quality of life, anxiety, depression, social and material deprivation, patients and oncological charactericitcs, and intercurrent pathologies
CHU Clermont-Ferrand
Clermont-Ferrand, France
substance use
Legal: alcohol, tobacco, electronic cigarette, psychotropic drugs (benzodiazepines, z-drugs, and opioids), CBD, and other susbtances Illegal: cannabis, and other drugs At least once in the past year, at least once in the past month, at least once in the past week, or at least once a day
Time frame: day 1
Pain severity
Brief pain inventory
Time frame: day 1
Neuropathic pain
DN4 interview questionnaire
Time frame: day 1
Analgesic use
Ongoing analgesic drugs
Time frame: day 1
Chemotherapy-induced peripheral neuropathy
QLQ-CIPN20 questionnaire
Time frame: day 1
Health-related quality of life and symptoms
QLQ-C30 questionnaire
Time frame: day 1
Anxiety and depression
HADS questionnaire
Time frame: day 1
Material and social deprivation
EPICES questionnaire
Time frame: day 1
Sociodemographic characteristics of patient
age, sex, height, weight, body mass index, area of residence (urban or rural), socio-professional status (INSEE), and department
Time frame: day 1
Oncological characteristic
type of cancer, date of cancer diagnosis, and type of treatment (received and/or ongoing)
Time frame: day 1
Intercurrent pathologies
open question
Time frame: day 1
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