Needless Laser Injector for Antiaging Effect of Dermal Filler

Seoul National University Bundang Hospital24 enrolled

Overview

The investigators aimed to evaluate the efficacy and safety of needless laser injector for antiaging effect of dermal filler.

A 24-week prospective, single-center, assessor-blinded, randomized, split-face study was conducted to compare the clinical efficacy and safety of needless laser injector versus needle injection for anti-aging effect of dermal filler.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Aging Problems

Interventions

needless laser injector (Mirajet)DEVICE

Mirajet injection was performed 2-3 passes until a total of 2cc of diluted PLA/HA solution was completely injected to the one half of the face.

needle injectionDEVICE

For traditional method of needle injection, intradermal injection using multi-puncture/micro-papule technique was used. A series of injections at 0.5-1 cm apart was performed on one half of the face so that a total of 2cc of diluted PLA/HA solution was injected.

Eligibility

Sex: ALLMin age: 25 YearsMax age: 60 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * patients who wanted to improve facial skin aging Exclusion Criteria: * a history of skin rejuvenation treatment (including filler, botulinum toxin, lasers, chemical peeling, and topical retinoid) within 6 month prior to the start of the study * having a plan for skin rejuvenation treatment during the study * current pregnancy or breastfeeding * an allergy to polylactic acid (PLA) or hyaluronic acid (HA) * uncontrolled medical diseases

Locations (1)

Seoul National University Bundang Hospital

Seongnam, South Korea