Antepartum hemorrhage (APH) due to placenta previa is an important cause of worldwide perinatal mortality and maternal morbidity in pregnant women
Antepartum hemorrhage (APH) due to placenta previa is an important cause of worldwide perinatal mortality and maternal morbidity in pregnant women. No medication is of specific benefit to a patient with placenta previa. Tocolysis may be cautiously considered in some circumstances in order to administer antenatal corticosteroids. A review article concluded that there is no improvement in perinatal outcome with prolonged tocolytics, and tocolysis beyond 48 hours is not clinically indicated.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
146
Active group will receive 1gm Tranexamic acid 12 hourly for 48 hours
Placebo group 30ml will be received 12 hourly for 48 hours
Ariana kh. Jawad
Erbil, Kurdistan Region, Iraq
Kurdistan Board for Medical speciality
Erbil, Kurdistan Region, Iraq
To stope or decrease vaginal bleeding
Receiving Tranexamic acid decreases or stops vaginal bleeding in women with placenta previa
Time frame: Up to time of delivery
Prolong pregnancy to 36 weeks
Decreased vaginal bleeding may prolong pregnancy
Time frame: Up to delivery of the fetus
Favorable perinatal outcome
Delivery of active newborn at or more than 36 weeks gestation
Time frame: 7 days post partum
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