The Effects of a 5-Step Skin Regimen on Pigmentation and Appearance Related Biophysical Properties

Integrative Skin Science and Research36 enrolled

Overview

This study is to analyze the effects of a 5-step skin care regimen on various skin parameters such as pigmentation, and firmness and elasticity of the skin around the eyes. The 5 facial products in the regimen are a cleansing balm, a toner, a serum, a moisturizer. and an eye cream.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Wrinkle

Interventions

Cleansing BalmOTHER

DermResults Cleansing Balm w/ Avocado Oil twice daily

Toning EssenceOTHER

DermResults Advanced Toning Essence w/ Mineral Booster twice daily

Facial SerumOTHER

DermResults Advanced Serum w/ Hyaluronic Acid twice daily

Eligibility

Sex: ALLMin age: 35 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Men and women between the ages of 35 years old and 65 years old. * Must have fine lines and wrinkles around the eyes. Exclusion Criteria: * Individuals who are pregnant or breastfeeding. * Prisoners * Adults unable to consent * Individuals who have changed any of their hormonal based contraception within 3 months prior to joining the study. * Subjects using any topical retinoid, hydroquinone, kojic acid, bakuchiol, hyaluronic acid or benzoyl peroxide containing topical product within 2 weeks of starting study or any subject unwilling to refrain from washout prior to enrollment. * Subjects with any facial treatments in the past 6 months and who are unwilling to withhold facial cosmetic treatments during the study including botulinum toxin, injectable fillers, microdermabrasion, intense pulsed light (IPL), peels, laser treatments, acid treatments, tightening treatments, facial plastic surgery, or any other medical treatment administered by a physician or skin care professional which is designed to improve the appearance of facial skin. * Current tobacco smoker or a tobacco smoking history of greater than 10 pack-years.

Locations (1)

Integrative Skin Science and Research

Sacramento, California, United States

Outcomes

Primary Outcomes

Appearance of facial wrinkles

Change in wrinkle severity measured by photographic analysis (BTBP 3D Camera System)

Time frame: 8 weeks

Change in skin pigmentation in the undereye area

Change in skin pigmentation in the undereye area by Skin colorimetric analysis of pigment

Time frame: 8 weeks

Secondary Outcomes

Skin hydration

Change in skin hydration by SkinMoistureMeterSC measurement

Time frame: 1 week

Skin hydration

Change in skin hydration by SkinMoistureMeterSC measurement

Time frame: 4 weeks

Skin hydration

Change in skin hydration by SkinMoistureMeterSC measurement

Time frame: 8 weeks

Transepidermal water loss

Change in transepidermal water loss measurement with Vapometer

Time frame: 1 week

Transepidermal water loss

Change in transepidermal water loss measurement with Vapometer

Time frame: 4 weeks

Transepidermal water loss

Change in transepidermal water loss measurement with Vapometer

Time frame: 8 weeks

Skin volume

Change in skin volume/plumpness by photographic image analysis with BTBP 3D Camera System

Data from ClinicalTrials.gov

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