Retention, Stability and Performance Assessment of Denture Fixatives Versus no Fixative Control

Inclusion Criteria: 1. Participants with a completely edentulous maxillary \[UPPER\] arch restored with a conventional full acrylic-based complete denture and dentate, partial, or full edentulous mandibular \[LOWER\], which may be restored with a stable complete, partial or implant supported denture 2. For complete denture wearers, maxillary \[UPPER\] dentures must be completely removable standard acrylic dentures, which are at least moderately well-fitting at the screening visit (modified (Olshan) Kapur Index: retention score ≥2, stability score ≥2) 3. Male or female participants aged between 18 and 85 years at the time of signing the informed consent form 4. Participants must have been using dentures daily for at least 6 months prior to the screening visit 5. Dentures must have been made in the last 5 years; 6. Dentures must be well-made based on design and construction in the opinion of the clinician 7. No clinically significant and relevant abnormalities in medical history or upon oral examination Exclusion Criteria: 1. Female participants who are pregnant as confirmed by a positive pregnancy test (urine) or are lactating (applicable to female participants of childbearing potential) 2. Daily doses of medication that might interfere with the ability to perform the study according to protocol or affect study assessments, for example, bisphosphonates (oral or intravenous) (as determined by the Investigator) 3. Known or suspected intolerance or hypersensitivity to the study materials (or closely related compounds) or any of their stated ingredients 4. Any clinically significant or relevant oral abnormality (e.g., temporomandibular joint \[TMJ\] problems), or recent (within last 6 months) oral surgery / intervention, or oral health concern that, in the opinion of the investigator, could affect the participant's participation in the study 5. Participants with maxillofacial defects covered by prosthetics 6. Self-reported and/or visual manifestations of severe dry mouth (xerostomia) that may affect denture retention in the opinion of the Investigator 7. Participants with oral soft tissue examination findings such as stomatitis, open sores, ulcers, lesions, redness or swelling or associated lymphadenopathy