The Use of EndoFlip as a Clinical Tool for the Prediction of Postoperative GERD After Sleeve Gastrectomy

Laval University100 enrolled

Overview

This study aims to determine if preoperative EndoFlip measurement can effectively predict postoperative GERD-related quality of life and lower esophageal acid exposure.

Enrolled patients will be subjected to a pre-operative gastroscopy, 48-Hour Bravo pH study and EndoFlip. In addition, each patient will complete a GERD-related quality of life questionnaire (GERD-HRQL scale). One year after surgery, patients will undergo a follow up a gastroscopy, pH study, EndoFlip and the same quality of life questionnaire to predict the incidence of postoperative GERD and determine the effect of sleeve gastrectomy.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

100

Conditions

Gastroesophageal Reflux Sleeve Gastrectomy Bariatric Surgery Complication

Interventions

sleeve gastrectomyPROCEDURE

Patients will be recruited for a sleeve gastrectomy according to the guidelines of the National Institute of Health.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age between 18 and 65 years old Exclusion Criteria: * Hiatal hernia \> 2 cm at preoperative gastroscopy * Erosive esophagitis at preoperative gastroscopy * Barrett's metaplasia/dysplasia at preoperative gastroscopy * Revision surgery before the end of the study * Pregnancy during the study period * Actively bleeding esophageal varices

Outcomes

Primary Outcomes

New-onset of gastroesophageal reflux disease

total time of esophageal acid exposure (minutes)

Time frame: 12 months postoperatively

Central Contacts

Ringuette Vickie

CONTACT

15147102044 vickie.ringuette@usherbrooke.ca

Data from ClinicalTrials.gov

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