Infection is one of common risk factors for relapsing of idiopathic membranous nephropathy (IMN). However, it is still unclear wheather COVID-19 infection can induce the relapsing of IMN. Herein, in this prospective, multi-center, cohort study, the investigator enrolled the IMN patients with COVID-19 infection. All subjects will be followed for three months with four visits at 1, 2 and 3 months. Then the investigator will compare the rate of replase of IMN in the two groups to evaluate the association of COVID-19 infection and replapse of IMN.
Study Type
OBSERVATIONAL
Enrollment
130
Beijing Friedship Hospital
Beijing, Beijing Municipality, China
RECRUITINGBeijing Pinggu Hospital
Beijing, Beijing Municipality, China
RECRUITINGBeijing Liangxiang Hospital
Beijing, Beijing Municipality, China
RECRUITINGprimary outcome
relaspe of nephrotic syndrome: proteinuria\<0.3g/d, serum albumin\>30g/l, serum creatitine below 111 μmol/l
Time frame: 3 months
secondary outcome
relaspe of nephrotic syndrome: proteinuria\<3.5g/d (decreased over 50% of baseline), serum albumin\>30g/l, steady serum creatitine (fluctuated less than 20% of baseline), meet the above criteria over 2 times
Time frame: 0.5, 1, and 2 months
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