The purpose of this study is to evaluate adverse events and tolerability of single and multiple doses of ABBV-903, and to assess how the drug moves through the body in healthy adult volunteers.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
104
Acpru /Id# 251279
Grayslake, Illinois, United States
Maximum Observed Plasma Concentration (Cmax)
Cmax will be assessed.
Time frame: Baseline to Day 36
Time to Cmax (Tmax)
Tmax will be assessed.
Time frame: Baseline to Day 36
Apparent Terminal Phase Elimination Constant (β)
Apparent terminal phase elimination constant (β) will be assessed.
Time frame: Baseline to Day 36
Terminal Phase Elimination Half-life (t1/2)
Terminal phase elimination half-life (t1/2) will be assessed.
Time frame: Baseline to Day 36
Area Under the Plasma Concentration-time Curve (AUC)
AUC will be assessed.
Time frame: Baseline to Day 36
Area Under the Plasma Concentration-time Curve from Time 0 Until the Last Measurable Concentration (AUCt)
AUCt will be assessed.
Time frame: Baseline to Day 36
Area Under the Plasma Concentration-time Curve from Time 0 Until Infinity (AUCinf)
AUCinf will be assessed.
Time frame: Baseline to Day 36
Number of Participants with Adverse Events (AEs)
An AE is defined as any untoward medical occurrence in a patient or clinical investigation participant administered a pharmaceutical product which does not necessarily have a causal relationship with this treatment.
Time frame: Baseline to Day 66
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