Discovering Novel Cancer Treatment Options Using a Comprehensive NGS-based Molecular Testing Panel in the Community Setting ("DINOSAur")

Inclusion Criteria: * Patients who have given informed consent in accordance with the methods and procedures of this study * Diagnosis of cancer (stage 3 and stage 4; solid tumors only) requiring medical care * Patients who have not received treatment related to his/her cancer * Patients who are willing to sign a release of medical records to the research team * Male and female patients ≥18 years of age * Patients under oncology care of a participating site * Sufficient clinical status for collection of biospecimen samples within usual care * Patients who have insurance coverage for CMT Exclusion Criteria: * Patients considered minors in the jurisdiction where the protocol is conducted. * Patients who are prisoners and pregnant women. * Patients who cannot provide consent and did not sign a power of attorney.