Prone position ventilation was used 220 times in 44 out of 68 patients with severe COVID-19 induced ARDS treated with VV-ECMO. PPV treated patients did not benefit from PPV and the incidence of PPV related adverse events was high
Purpose: To describe the use and effects of prone position ventilation (PPV) in patients with COVID-19 induced Adult Respiratory Distress Syndrome (ARDS), treated with Veno-Venous Extracorporeal membrane oxygenation (VV-ECMO). Methods: Nationwide retrospective analysis of all COVID-19 patients in Denmark from March 2020 - December 2021with severe ARDS and need of VV-ECMO treatment. Data on the number of patients treated with PPV, number of PPV-events, timing, the time spent in prone position, physiological response types, adverse events and outcomes are reported.
Study Type
OBSERVATIONAL
Enrollment
68
Turning the patient prone for 16 hours
Aarhus University Hospital, CardioThoracic Intensive care Unit
Aarhus, Denmark
University Hospital Rigshospitalet, department of CardioThoracic Anaesthesia and Intensive Care
Copenhagen, Denmark
90 day mortality
all cause mortality 90 days after ECMO start
Time frame: 90 days
Time-to-wean
Time from ECMO start to succesful weaning from ECMO
Time frame: From start of ECMO treatment to succesful weaning from ECMO
Recruitment Response to prone position ventilation
lung recruitment
Time frame: from prone position start to prone position end
Oxygenation Response to prone position ventilation
Oxygenation
Time frame: from prone position start to prone position end
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