This is a randomized controlled trial comparing density gradient centrifugation and microfluidic sperm sorting in patients undergoing intrauterine insemination to evaluate cumulative pregnancy outcomes.
Study participants will be randomized to either standard sperm preparation (density gradient centrifugation) versus sperm preparation with the Zymot Multi sperm preparation device for their three month intrauterine insemination treatment course. Patients will follow standard treatment plans designed by their fertility physician and will be followed until referred for prenatal care at 8-10 weeks of pregnancy to determine pregnancy outcomes.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
270
Sperm preparation with Zymot Multi sperm preparation device
Sperm preparation with density gradient centrifugation
UCSF Center for Reproductive Health
San Francisco, California, United States
RECRUITINGCumulative clinical pregnancy rate
The clinical pregnancy rate by treatment group over the course of IUI treatment
Time frame: 3 treatment cycles, an average of 5 months
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.