The aim of this study is to evaluate the efficacy between dienogest and danazol.
Objective: Women with adenomyosis or endometripsis are often suffered from dysmenorrhea or menorrhagia. Dienogest and danazol are frequently used for the treatment of endometriosis. However, there was no literature mentioned about which medication is better for the treatment of endometriosis. Thus, the aim of this study is to evaluate the efficacy between dienogest and danazol. Methods: All consecutive women, who have endometriosis, will be randomized to receive dienogest or danazol treatment, and will assess symptoms severity, receive CA125 examination, sonographic examination at baseline, 4 weeks and 16 weeks after treatment.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
120
Department of Obstetrics and Gynecology, Far Eastern Memorial Hospital
Banqiao District, New Taipei, Taiwan
RECRUITINGThe change of severity in dysmenorrhea
Between-group difference in the score of global response assessment of dysmenorrhea
Time frame: 16 weeks
The change of severity in urinary symptoms
Between-group difference in the score of UDI-6
Time frame: 16 weeks
The change of severity in quality of life related to urinary symptoms
Between-group difference in the score of IIQ-7
Time frame: 16 weeks
The change of severity in menstrual amount
Between-group difference in the score of global response assessment of menstrual amount
Time frame: 16 weeks
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