Different Local Anesthetic Volumes for TPVB in Post-thoracotomy Analgesia

Ankara City Hospital Bilkent75 enrolled

Overview

Thoracotomy is one of the most painful operations known. Therefore, it causes severe acute pain. If pain is not controlled, it increases the frequency of postoperative pulmonary complications and postoperative morbidity. It can even cause chronic pain in the future. Thoracic epidural analgesia (TEA) is the gold standard method in the treatment of pain after thoracotomy. Thoracic paravertebral block (TPVB) is known as the most effective method after TEA. The fact that TPVB has fewer side effects than TEA increases the use of TPVB. There is no consensus on the dose of analgesia in studies. In the literature, volumes between 20 ml and 30 ml are frequently used for TPVB in recent years. This study, it was aimed to compare the efficacy of 20 ml, 25 ml, and 30 ml volumes of TPVB with local anesthetic at the same concentration (0.25% bupivacaine) on postoperative analgesia in patients undergoing thoracotomy.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Thoracic Paravertebral Block Thoracotomy Postoperative Analgesia

Interventions

TPVB with 20 mlPROCEDURE

The thoracic paravertebral block will be applied to the patients with 20 ml of 0.25% bupivacaine under real-time ultrasound guidance.

TPVB with 25 mlPROCEDURE

The thoracic paravertebral block will be applied to the patients with 25 ml of 0.25% bupivacaine under real-time ultrasound guidance.

TPVB with 30 mlPROCEDURE

The thoracic paravertebral block will be applied to the patients with 30 ml of 0.25% bupivacaine under real-time ultrasound guidance.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * 18 to 80 years old * American Society of Anesthesiologists (ASA) physical status I-II-III * BMI 18 to 40 kg/m2 * Elective thoracotomy surgery Exclusion Criteria: * Patient refusing the procedure * Emergency surgery * History of chronic opioid or analgesic used

Outcomes

Primary Outcomes

Pain Scores

Pain will be assessed at the first-hour rest and while coughing using the visual analog scale on a scale from 0 (no pain) to 10 (worst pain).

Time frame: 1st hour after surgery

Pain Scores

Pain will be assessed at the 2nd-hour rest and while coughing using the visual analog scale on a scale from 0 (no pain) to 10 (worst pain).

Time frame: 2nd-hour after surgery

Pain Scores

Pain will be assessed at the 4th-hour rest and while coughing using the visual analog scale on a scale from 0 (no pain) to 10 (worst pain).

Time frame: 4th-hour after surgery

Pain Scores

Pain will be assessed at the 12th-hour rest and while coughing using the visual analog scale on a scale from 0 (no pain) to 10 (worst pain).

Time frame: 12th-hour after surgery.

Pain Scores

Pain will be assessed at the 24th-hour rest and while coughing using the visual analog scale on a scale from 0 (no pain) to 10 (worst pain).

Time frame: 24th-hour after surgery.

Pain Scores

Pain will be assessed at the 48th-hour rest and while coughing using the visual analog scale on a scale from 0 (no pain) to 10 (worst pain).

Time frame: 48th-hour after surgery.

Secondary Outcomes

Morphine Consumption

Morphine consumption for 24 hours will be recorded

Time frame: 24 hours after surgery

Different Local Anesthetic Volumes for TPVB in Post-thoracotomy Analgesia

Overview

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Primary Outcomes

Secondary Outcomes

Central Contacts