Effectiveness of Outpatient Intravenous Diuretic Therapy for Treatment of Worsening Heart Failure (OUTPATIENT-WHF)

Inclusion Criteria: 1. ≥18 years of age 2. Presentation to a Duke outpatient clinic with heart failure requiring IV diuretics, as per clinician judgement 3. Able to provide signed informed consent 4. Successful completion of EuroQOL-5 dimensions survey Exclusion Criteria: 1. Managing clinician without equipoise for initial outpatient treatment strategy versus initial hospitalization-based treatment strategy for heart failure, and decline to accept randomization. 2. Patient without equipoise for initial outpatient treatment strategy versus initial hospitalization-based treatment strategy for heart failure, and decline to accept randomization. 3. History of left ventricular assist device or heart transplantation 4. End-stage kidney disease requiring chronic dialysis therapy 5. New diagnosis of heart failure 6. Pregnant or breast-feeding 7. Fever \>101.0 degrees Fahrenheit at screening 8. Any other condition that in the judgment of the investigator would jeopardize the patient's compliance with the study protocol