Cardiovascular and Cerebrovascular Control in Healthy Subjects

IRCCS Policlinico S. Donato60 enrolled

Overview

The aim of the study is to evaluate autonomic function and cerebrovascular control in 60 healthy subjects by means of noninvasive analysis of time series variability. To this extent, heart period, systolic and mean arterial blood pressure, cerebral blood velocity, peripheral resistances, respiration will be recorded from subjects during an orthostatic challenge. The interactions between autonomic cardiovascular function, cerebrovascular and peripheral control will be evaluated exploiting the most advanced signal processing techniques.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Healthy Autonomic Nervous System Cerebral Autoregulation

Interventions

active standingDIAGNOSTIC_TEST

Data are acquired with patients resting in supine position for 10 minutes and for 10 minutes during active standing

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * age \>18 * sinus rhythm * informed consent signed Exclusion Criteria: * age \<18 * presence of autonomic nervous system diseases or dysfunctions

Locations (1)

IRCCS Policlinico San Donato

San Donato Milanese, Milan, Italy

RECRUITING

Outcomes

Primary Outcomes

Evaluate the state and interactions of autonomic function and cerebrovascular control

Time frame: 12 months

Central Contacts

Vlasta Bari, PhD

CONTACT

+390252774381 vlasta.bari@grupposandonato.it

Data from ClinicalTrials.gov

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