A Prospective Study of Surgical Treatment Strategies for Chordoma

Xuanwu Hospital, Beijing100 enrolled

Overview

Chordoma is a rare but locally invasive cancer that arises from the embryonic notochord. Total resection is challenging in mobile spine because of the complex anatomy and bone invasion.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

100

Conditions

Chordoma of Spine Surgery

Interventions

Resection surgeryPROCEDURE

Patients undergo resection surgery in our hospital.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Between the ages of 18 and 70 ys, * With a diagnosis of chordoma confirmed by pathology, * Undergone surgical treatment in our hospital, * Available for clinical follow-up and agree to long-term clinical follow-up and sign informed consent. Exclusion Criteria: * Suffer from other tumors, * Suffer from cardiovascular disease, cerebrovascular disease, or immune system disease.

Locations (1)

Xuanwu Hospital, Capital Medical University

Beijing, China

RECRUITING

Outcomes

Primary Outcomes

Excision Extension

Clinical and radiographic assessments of excision extension of tumor.

Time frame: 1 week after surgery.

Secondary Outcomes

OS (Overall Survival)

Overall Survival of patient underwent surgery.

Time frame: 2 years

PFS (Progression-Free Survival)

Progression-Free Survival of patient underwent surgery.

Time frame: 2 years

DFS (Disease Free Survival)

Disease Free Survival of patient underwent surgery.

Time frame: 2 years

ORR (Objective Response Rate)

Objective Response Rate of patient underwent surgery.

Time frame: 2 years

Data from ClinicalTrials.gov

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