Hypoplastic Left Heart Syndrome: Subendocardial Viability After Norwood Palliation

IRCCS Policlinico S. Donato6 enrolled

Overview

This project has several objectives ranging from clinical data analysis to computational simulations as listed below: 1. Retrospective review of all patients with HLHS treated surgically and followed medically at the IRCCS Policlinico San Donato aiming to assess the SEVR after each step of Norwood palliation to analyze its influences on: * Mortality; * Occurrence of adverse events; * Outcome of the three-staged palliation; 2. Creation of a prospective registry that will enroll all patients surgically treated for HLHS at the IRCCS Policlinico San Donato.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Hypoplastic Left Heart Syndrome

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * Pediatric patients (age ≤18 years) with the diagnosis of hypoplastic left heart syndrome who underwent the Norwood palliation at the IRCCS Policlinico San Donato. Exclusion Criteria: * Patients with any type of atrioventricular discordance. * Pediatric patients (age ≤18 years) with the diagnosis of hypoplastic left heart syndrome who underwent the Norwood palliation at the IRCCS Policlinico San Donato before March 2019.

Locations (1)

IRCCS Policlinico San Donato

San Donato, Milano, Italy

Outcomes

Primary Outcomes

Mortality during the hospital stay and after the discharge

death, cardiovascular arrest

Time frame: 5 year

Secondary Outcomes

Number of adverse events registered during the follow-up.

Patients will be followed prospectively with their normal routine cardiological follow-up for 5 years

Time frame: 5 year

Data from ClinicalTrials.gov

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