Effects of RF Microneedle on Photoaging Skin

Ajou University School of Medicine15 enrolled

Overview

Melasma relapse is almost common after discontinuation of conventional treatment. Recent studies have suggested that photoaging dermis is main pathomechanism of melasma emphasizing stromal targeting therapy. Therefore, we investigated maintenance effect of microneedle radiofrequency (RF) for melasma treatment.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Pigmentation Pigmentation Disorder

Interventions

RF MicroneedleDEVICE

Pulsed-type RF device in bipolar mode with 25 non-insulated microneedles every 2 weeks for 6 month

Combination creamDRUG

5% hydroquinone, 0.003% tretinoin, and 1% hydrocortisone twice daily for 2 months

Eligibility

Sex: FEMALEMin age: 20 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Adult more than 19 years old * Melasma clinically diagnosed by three dermatologists Exclusion Criteria: * Aesthetic medical procedures in three months prior to the study * Use of topical depigmenting agents in three months prior to the study * Pregnant or lactating

Locations (1)

Ajou University Hospital

Suwon, South Korea

Outcomes

Primary Outcomes

Change of modified melasma area severity index score

Time frame: Every 1 month up to 8 months

Change of lightness value

Change of lightness value by a chromometer

Time frame: Every 1 month up to 8 months

Data from ClinicalTrials.gov

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