Pharmacokinetic Characteristics of Subjects with Hepatic Insufficiency and Healthy Subjects

Inclusion Criteria: * The presence of cirrhosis was confirmed by CT, magnetic resonance imaging (MRI), liver biopsy or noninvasive hepatic fibrosis test. * The subject was determined to have liver insufficiency based on A Grade A or B on the Child-Pugh scale. * If the subject has hepatic encephalopathy, the investigator determines that the current condition will not interfere with the subject's ability to provide appropriate informed consent. Exclusion Criteria: * Previous or present history of respiratory, blood, cardiovascular, digestive, urinary, endocrine and metabolic, neurological or psychiatric disorders with clinical manifestations. * People with an allergic disposition (multiple drug and food allergies) or who, as determined by the investigator, are likely to be allergic to the investigational drug product or any component of the investigational drug product. * A history of gastrointestinal surgery or excision may interfere with oral drug absorption and/or excretion * Patients with abnormal vital signs at screening visit and baseline visit: ear temperature \> 37.5℃, pulse rate \> 100 beats/min or \< 50 beats/min, systolic blood pressure ≥140 mmHg or \< 90 mmHg, diastolic blood pressure ≥90 mmHg or \< 50mmHg. * Participated in clinical studies of any drug or medical device within 3 months prior to screening, and participated in clinical studies of drug for 3 or more times within the last year. * Severe infection, trauma, or major surgery within 4 weeks prior to screening, or clinically significant (as determined by the investigator) acute illness such as gastrointestinal disease, infection (e.g. respiratory or central nervous system infection, and idiopathic peritonitis) within 2 weeks prior to screening. * Had used any prescription drugs, Chinese herbs, or over-the-counter drugs (except birth control pills, acetaminophen, and topical over-the-counter preparations) in the 2 weeks prior to enrollment; Unless the principal investigator (PI) and the sponsor agree that the drug used has no impact on the safety and PK results of the study; If the combined drug has a longer half-life (more than 3 days), the required time interval will be longer and should be at least 5 half-lives of the drug. * Smoking averaged more than 5 cigarettes per day in the 3 months prior to screening, or could not stop using any tobacco products during the study period. * Persons who consumed more than 14 units of alcohol per week (1 unit = 360mL beer, 150 mL wine or 45 mL 40% spirits) in the 3 months prior to the screening period, or who had a positive alcohol breath test (screening period or baseline period), or who could not abstain during the study period. * Test positive for hepatitis B (HBV) surface antigen, hepatitis C virus (HCV) antibody, anti-human immunodeficiency virus (HIV) antibody or treponema pallidum antibody. * Subjects with a history of substance abuse (e.g., morphine, dimethyldioxyamphetamine, methylamphetamine, tetrahydrocannabinol, ketamine, cocaine) or who screened positive for substance abuse. * Those who received the vaccine within 30 days prior to administration or who planned to receive the vaccine during the study period. * Donors who donated \> 400 mL within 3 months prior to the screening period or \> 200 mL within 4 weeks or planned to donate blood during the study period. * Patients with difficulty in venous blood collection. * Vigorous exercise should not be prohibited within 48 hours before and during the study period. * It is expected that patients may be scheduled for surgery or hospitalization during the study. * Any other circumstances which, in the opinion of the investigator, may affect the subject's ability to provide informed consent or to follow the protocol of the study, to complete the study in accordance with the study procedure, or the subject's participation in the study may affect the results of the study or his or her own safety.