This study is being conducted with the aim of comparing the time to bone healing after surgery for fragility fractures of proximal femur between patients receiving strontium ranelate and placebo. Patients recruited are of 60 years of age and above. Bone healing will be assessed on clinical parameters when patient is able to ambulate full weight bearing without pain and on Xray images using RUSH score. Moreover Dexa scan will be performed pre-operatively and at 3 months postoperatively. The findings of this study will help in setting up guidelines for treatment of fragility proximal femur fractures in our population as there is still paucity of literature on effectiveness of strontium ranelate from our part of the world.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
100
Dual mode of action, anabolic and anti-resorptive
Placebo look alike drug
Aga Khan University Hospital
Karachi, Sindh, Pakistan
RECRUITINGchange in Radiological healing on radiographs
Difference in RUSH (Radiological Healing score for hip) score measured at 12 weeks and 24 weeks
Time frame: 12 weeks and 24 weeks
change Bone mineral density through DEXA scan
Difference in bone density T scores between pre-op and 3 months studies
Time frame: pre-operatively or peri-admission and at 3 months
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