The aim of this study is to show that the SPECT/CT whole body recording procedure lasting less than or equal to 30 minutes in a VERITON-CT™ camera, can be substituted for the classic procedure, giving at least equivalent information in searches for primary or metastatic neoplastic lesions.
Patients with thyroid cancer treated with iodine 131 will receive an iodine 131 activity of between 1100 and 3700 MBq delivered as a capsule orally to eliminate the remaining thyroid tissue. Hormone replacement therapy (HRT) is then started to correct the hypothyroidism. 3 days later, a 2D whole body recording will be associated with complementary Single Photonic Emission Computed Tomography CT scans (SPECT/CT). It enables visualising the fixation of iodine 131, provides information on the thyroid remnants left in place during surgical thyroidectomy and to carry out an extension assessment by visualizing the possible presence of metastases fixing iodine at the level of the regional lymph nodes or many distant sites, in particular, lung and bone. In VERICATH study, the hypothesis is that this classic procedure could be advantageously replaced by a single full-body SPECT/CT recording of a limited duration (≤ 30 minutes), obtained with a camera state-of-the-art semiconductor device called the VERITON-CT™ (Spectrum Dynamics Medical) camera.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
OTHER
Masking
NONE
Enrollment
77
A SPECT-CT whole body in VERITON-CT camera is added after the conventional procedure recorded in Anger camera
Chru Nancy Brabois
Vandœuvre-lès-Nancy, France
RECRUITINGCompare post-therapy imaging performed with the two procedures
Type of lesions * Lesions * The nature of the lesion(s): thyroid residue and/or lymph node lesion and/or metastases (distant lesions). * Number of lesions in conventional camera and in VERITON-CT™ camera.
Time frame: 18 months
Compare the two procedures in terms of cancer status result.
Status of cancer
Time frame: 18 months
Determine the feasibility of a 3D quantification of the fixation of thyroid residues in a VERITON-CT™ camera
Measurement of absolute quantification with the 2 procedures
Time frame: 18 months
Evaluate the two exams in terms of ergonomics for technologists
Likert scale results
Time frame: 18 months
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