This is a randomized, parallel study that will be conducted on pediatric patients with CKD.
The study will be conducted on 90 pediatric patients with CKD who will be divided into 3 groups: Group l: 30 pediatric patients who will receive oral liposomal iron 30 mg/day for 12 weeks. Group 2: 30 pediatric patients who will receive oral iron supported iron 1 mg+ lactoferrin 100 mg/day for 12 weeks. Group 3: 30 pediatric patients who will receive IV iron dextran 50 mg/3 times weekly for 12 weeks.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
90
30 pediatric patients who will receive oral liposomal iron (Novoferr) 30 mg/day for 12 weeks.
30 pediatric patients who will receive oral iron supported Lactoferrin (Provan) 100 mg/day for 12 weeks.
30 pediatric patients who will receive IV iron dextran 50 mg /3 times weekly for 12 weeks.
Hemoglobin measure
Measure oxygen in blood by measuring hemoglobin by coloremetric assay
Time frame: 3 months
Biomarkers measure
changes in serum levels of biological biomarkers( measure IL-6, hepcidin and GDF-15 by ELISA assay).
Time frame: 3 months
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