High Flow Nasal Cannula After Esophagectomy

Cristian Deana320 enrolled

Overview

This study will compare the effect of HFNC versus standard oxygen administration after elective esophagectomy for cancer.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

320

Conditions

Esophageal Cancer Postoperative Pulmonary Atelectasis Postoperative Pneumonia Postoperative Pneumothorax Postoperative Infection of Incision Postoperative Acute Myocardial Infarction

Interventions

AIRVO2DEVICE

APPLICATION OF HIGH FLOW NASAL CANNULA OXYGEN FOR 48 HOURS AFTER ESOPHAGECTOMY

STANDARD CAREOTHER

APPLICATION OF OXYGEN THROUGH STANDARD CARE FOR 48 HOURS AFTER ESOPHAGECTOMY

Eligibility

Sex: ALLMin age: 18 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: * elective esophagectomy for cancer * METS≥4 * AGE 18-85 * Written informed consent Exclusion Criteria: * ASA\>3 * COPD≥ III stage according to GOLD criteria * FEV1\<50% * EF\<30% * NYHA\>2 * BMI\<17 or \>35 Kg/m2 * CKD with eGFR\<60 mL/min

Locations (1)

Azienda Sanitaria Universitaria Friuli Centrale

Udine, Italy

RECRUITING

Outcomes

Primary Outcomes

POST-OPERATIVE PULMONARY COMPLICATIONS

Describe the frequency of PPC that include: pneumonia, pleural effusion, pneumothorax, atelectasis, ARDS, aspiration pneumonia, trachea-bronchial lesion, air leak

Time frame: within 30 days after surgery

Secondary Outcomes

CARDIO-VASCULAR COMPLICATIONS

Describe the frequency of myocardial infarction, pulmonary edema, cardiac arrest, pulmonary embolism, deep venous thrombosis, stroke, pericardtis

Time frame: within 30 days after surgery

Central Contacts

CRISTIAN DEANA, MD

CONTACT

+393333745660 CRISTIAN.DEANA@ASUFC.SANITA.FVG.IT

Data from ClinicalTrials.gov

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