Effect of Recombinant Human Bone Morphogenetic Protein-2 With an Absorbable Collagen Sponge on Stability of Dental Implant: (Split Mouth Randomized Clinical Trial Study.

Inclusion Criteria: * Patients have good oral hygiene. * Systemic healthy individuals ,Age more than18 years. * Healed edentulous area for at least 6 months after tooth extraction (delayed implant protocol). * Patients have at least two missing teeth in the jaw (canine to 1st molar area) indicated for the dental implant. Exclusion Criteria: * Presence of systemic diseases preventing implantation. * Previous implantation or augmentation of the same region. * The need for additional bone augmentation procedures (such as maxillary sinus augmentation) * Partial or total edentulous ridge associated with a severe knife-edge ridge . * Acute infection or any pathological lesion a the implant site. * Allergy to one of the materials to be used during operation. * Pregnancy. * Radiation therapy, bisphosphonate drugs , Osteoradionecrosis.