Effects of Different Ventilatory Strategy on Intraoperative Atelectasis During Bronchoscopy Under General Anesthesia.

N/AUnknownNCT05720845

Guangzhou Institute of Respiratory Disease60 enrolled

Overview

This trial compares two different types of ventilation for the prevention of partial or complete collapsed lung (atelectasis) in patients undergoing interventional pulmonology procedures under general anesthesia. Ventilatory strategy to prevent reduce the intra-procedural development of atelectasis during interventional pulmonology procedures under general anesthesia.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

OTHER

Masking

NONE

Enrollment

Conditions

Lung Disorder

Interventions

VESPAPROCEDURE

Using Ventilatory strategy of prevent atelectasis for General Anesthesia.

conventional mechanical ventilationPROCEDURE

Conventional mechanical ventilation for General Anesthesia.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Adult patients undergoing interventional pulmonology procedures with radial probe endobronchial ultrasound (RP-EBUS) for peripheral lung lesions * Recent (\< 4 weeks) chest computed tomography (CT) performed prior to the bronchoscopy Exclusion Criteria: * Patients with baseline lung consolidation, interstitial changes or lung masses (\> 3 cm in diameter) in dependent areas of the lung (right/left \[R/L\] B6, 9, or 10 bronchial segments) as seen on most recent CT * History of primary or secondary spontaneous pneumothorax

Locations (1)

Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University

Guangzhou, Guangdong, China

Outcomes

Primary Outcomes

Presence or absence of new atelectasis for each segment

The proportion of patients identified as developing intraprocedural atelectasis by radial probe endobronchial ultrasound (RP-EBUS)

Time frame: During bronchoscopy, an average of 1 hour.

Secondary Outcomes

Ventilation-induced complications

Time frame: Within 48 hours of bronchoscopy

Bronchoscopy-induced complications

Time frame: Within 48 hours of bronchoscopy

Assess the regional ventilation distribution by Electrical impedance tomography (EIT)

Time frame: During bronchoscopy, an average of 1 hour.

Data from ClinicalTrials.gov

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