Although emerging evidence demonstrated that left bundle branch pacing (LBBP) is a promising alternative for patients with either a bradycardia or a heart failure pacing indication. However, a direct comparison of the safety, efficacy and LV systolic synchrony between LBBP and RVP regimens was rare. In this study, the investigators aim to conduct a comparison of the safety and effectiveness performance between these two pacing methods for patients with atrioventricular block (AVB). The investigators focused on AVB patients undergoing permanent pacemaker implantations from the 1st of January 2018 to the 18th of November 2021 at West China Hospital.
Right ventricular pacing (RVP) is the standard treatment for patients with continuous ventricular pacing needs. However, clinical studies have shown that RVP can cause electrical and mechanical dyssynchrony of the left ventricle and increase the risks of cardiac insufficiency, atrial fibrillation (AF) and death. Although emerging evidence demonstrated that left bundle branch pacing (LBBP) is a promising alternative for patients with either a bradycardia or a heart failure pacing indication. However, a direct comparison of the safety, efficacy and LV systolic synchrony between LBBP and RVP regimens was rare. In this study, the investigators aim to conduct a comparison of the safety and effectiveness performance between these two pacing methods for patients with atrioventricular block (AVB). The investigators focused on AVB patients undergoing permanent pacemaker implantations from the 1st of January 2018 to the 18th of November 2021 at West China Hospital.
Study Type
OBSERVATIONAL
Enrollment
1,000
After recording the His potential, the 3830-69 lead (Medtronic Inc., Minneapolis, MN USA) was sent 1-2 cm forward and downward to find the insertion point of the right side of intra-ventricular septum combined with the pre-rotation impedance and ECG changes. Ultimately, the tip was perpendicularly straightforward posited against the septum to the left septal side .
Right ventricular pacing (RVP) is the standard treatment for patients with continuous ventricular pacing needs.
West China Hospital, Sichuan University
Sichuan, Sichuan, China
RECRUITINGcomposed of all-cause mortality, lead failure and heart failure hospitalization (HFH) during the follow-ups
composed of all-cause mortality, lead failure and heart failure hospitalization (HFH) during the follow-ups
Time frame: through study completion, an average of 2.45 year
Lead failure
reintervention for increased pacing thresholds, lead dislocation or ventricular perforation after the initial implantation procedure
Time frame: through study completion, an average of 2.45 year
HFH
HFH was defined as the admission to hospital for \>24 hours with worsening symptoms and signs of heart failure and requiring one or more intravenous diuretics or intravenous inotropic medications
Time frame: through study completion, an average of 2.45 year
peri-procedure complication
included pericardial tamponade and pneumothorax
Time frame: through study completion, an average of 2.45 year
cardiac death
documented arrhythmogenic death, an unexpected presumed pulseles condition with the absence of an obvious noncardiac explanation, or a death due to congestive cardiac failure or structural heart disease
Time frame: through study completion, an average of 2.45 year
recurrent unexplained syncope
recurrent unexplained syncope
Time frame: through study completion, an average of 2.45 year
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