Effects of Hardaliye, a Fermented Grape Drink, on Oxidative Stress, Lipid Profile and Blood Pressure in Young Footballers

Medipol University36 enrolled

Overview

In the present study, the authors aimed to investigate the effects of hardaliye (grape juice) consumption on oxidative stress parameters, lipid profile and blood pressure in young football players.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

SINGLE

Enrollment

Conditions

Diet, Healthy Antioxidative Stress

Interventions

Grape juiceOTHER

Hardaliye (grape juice) is a fermented, traditional non-alcoholic beverage made from fresh grapes. It is mainly produced by the fermentation of grapes, sour cherry leaves and mustard seeds. Hardaliye was purchased from traditional producers in Turkey. Hardaliye Group consumed 250 ml/day of hardaliye (grape juice) for 28 days.

Placebo drinkOTHER

Placebo drink has carbohydrate, energy and sensory properties similar to hardaliye. Placebo Group consumed 250 ml/day of placebo drink

Eligibility

Sex: MALEMin age: 15 YearsMax age: 24 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Being a male football player playing in a team in the Elite Development League, * Participating in training with the team at least 5 days a week for 3 months, * Not consuming red wine, grape juice, and/or hardaliye regularly before the study was started, * Those who stayed in the sports facility where catering service was provided for breakfast, lunch and dinner were included in the study. Exclusion Criteria: * With chronic disease, * Smoker, * Those taking antioxidant supplements, * Non-cooperative subjects or unwilling to sign an informed consent and participate in the study.

Locations (1)

Istanbul Medipol University

Istanbul, Turkey (Türkiye)

Outcomes

Primary Outcomes

Change in total antioxidant capacity

Measurement of serum level of total antioxidant capacity (μmol Trolox eq/L).

Time frame: 28 days

Change in total oxidation status

Measurement of serum level of total oxidation status (μmol H2O2 eq/L).

Time frame: 28 days

Change in oxidative stress index

(Serum level of total oxidation status/serum level of total antioxidant capacity) × 100

Time frame: 28 days

Change in lipid parameters

Measurement of serum levels total cholesterol (mg/dl), HDL-cholesterol (mg/dl), LDL-cholesterol (mg/dl) and triglycerides (mg/dl).

Time frame: 28 days

Change in blood pressure

Measurement of systolic (mm Hg) and diastolic blood pressure (mm Hg)

Time frame: 28 days

Secondary Outcomes

Change in perceived exercise-induced pain

Perceived exercise-induced pain was determined using the 100-mm Visual Analog Scale. 100-mm Visual Analog Scale scores range from 0 (no pain) to 100 (most severe pain). A higher score indicates a higher perceived pain level.

Time frame: 28 days

Data from ClinicalTrials.gov

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