Propofol is one of the most commonly used sedative in endoscopic procedures, while its potency to induce respiratory depression may threaten patient safety. Remimazolam is known to less likely induce hemodynamic instability when compared to propofol, yet its favorable effects are not clearly evaluated in endoscopic procedures. Hence, this study aimed to compare hemodynamic effects of remimazolam and propofol, by evaluating oxygen reserve index (ORI) in patients scheduled for diagnostic gastric endoscopy.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
DOUBLE
Enrollment
70
Patients in this group receives 0.1mg/kg of remimazolam to induce sedation prior to endoscope insertion.
Patients in this group receives 0.5mg/kg of propofol to induce sedation prior to endoscope insertion.
Yonsei University Health System, Severance Hospital
Seoul, South Korea
Incidence of Oxygen Reserve Index (ORI) drop to 0.00 during sedation
Incidence of Oxygen Reserve Index (ORI) drop to 0.00 will be evaluated after sedative administration, until the end of endoscopic procedure.
Time frame: Evaluation begins after sedative administration until the end of endoscopic procedure.
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