Electrocardiograph Changes and Holter Abnormalities in Children With Predialytic Chronic Kidney Disease

Sohag University50 enrolled

Overview

CKD is a strong risk factor for cardiovascular disease and mortality , As in adults, cardiovascular disease occurs in some children with CKD before they reach ESRD as well as after

This work aims to study the electrophysiological changes in cardiovascular system in children with predialytic CKD. ECG is important in detection of cardiac rhythm abnormalities, cardiac conduction defects and detection of myocardial ischemia

Study Type

OBSERVATIONAL

Enrollment

Conditions

Predialytic Chronic Kidney Disease

Interventions

HolterDEVICE

24 hour electrocardiography

Eligibility

Sex: ALLMin age: 1 YearMax age: 15 Years

Medical Language ↔ Plain English

Inclusion Criteria: Age 1 to 15 year children with predialytic chronic kidney disease GFR.\>15 ml\\min per 1.73m2 , stages 1, 2, 3, 4 according to (KDOQI stages). Exclusion Criteria: * Age \>15 year On regular dialysis GFR\<15 ml\\min per 1.73m2, Stage 5 according to (KDOQI stages). Children with known cardiovascular disease or known arrhythmia Patients on the potential medication affecting ECG result as B-blocker, antipsychotics , antidepressant

Locations (1)

Sohag faculty of medicine

Sohag, Egypt

RECRUITING

Outcomes

Primary Outcomes

Heart rate variability

Sinus tachycardia or bradycardia

Time frame: One year

changes in QT interval

Prolonged QT interval in ECG

Time frame: One year

QRS duration

Increase or decrease in ECG

Time frame: One year

Central Contacts

Wethab K Mohamed, Pediatric resident

CONTACT

+2001090090162 Wethab011226@med.sohag.edu.eg

Shaimaa M Mahmoud, Assistant professor

CONTACT

Data from ClinicalTrials.gov

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