In this randomized controlled trial the effect of 4 months of multi-component (strength, balance, cognition, endurance) exercise training intervention on measures of neuromuscular performance, cognition, and endurance as well as neural adaptations on a central and peripheral level is investigated. 40 subjects are recruited that are generally health and between 60 and 80 years of age. The interventions is based around exercises, where different tasks have to be solved simultaneously rather than serially, as has previously been done.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
48
Multi-component (strength, balance, cognition) exercise training.
Participants are being given the standard recommendations how much exercise and what type older adults should do.
Participants are instructed to write down their physical activity and exercises.
Departement für Sport, Bewegung und Gesundheit
Basel, Canton of Basel-City, Switzerland
Isometric knee-extension strength
Strength in torque (N\*m) of the quadriceps femoris muscle. Measured on an isokinetic device in an isometric condition.
Time frame: 16 weeks
Isometric knee-flexion strength
Strength in torque (N\*m) of the hamstring muscle group measured on an isokinetic device in an isometric condition.
Time frame: 16 weeks
Cognitive Processing Speed
Eriksen flanker task performance measured be reaction speed in milliseconds and accuracy in percentage.
Time frame: 16 weeks
Cognitive Impulsiveness
Go / No-Go task performance measured by reaction speed in milliseconds and accuracy in percentage.
Time frame: 16 weeks
Balance Performance
Staying as stable as possible during ten seconds in tandem stance eyes open condition. Center of pressure sway path length in mm and average sway speed in m/s is calculated.
Time frame: 16 weeks
Hand Grip Strength
Using a handheld dynamometer with an extended arm squeezing as hard as possible. Measured in N.
Time frame: 16 weeks
Counter movement jump power
Measured on a force plate participants are instructed to jump as high as possible with their hands akimbo. Peak of the time-power curve in Watts.
Time frame: 16 weeks
Blood Pressure
Blood pressure cuff on the right arm at the height of the aorta. Measured in mmHG.
Time frame: 16 weeks
Pulse Wave Velocity
Estimated from a mobile blood pressure cuff (mobil-O-graph) on the right arm. Measured in m/s.
Time frame: 16 weeks
Retinal vessel diameter
A photo is made from the retinal vessels with a static vessel analyzer (camera)through the eye and the vessel diameters are measured in mikrometers.
Time frame: 16 weeks
Quality of Life Questionnaire
26 item questionnaire (WHOQOL-Bref). Every answer is rated on a scale from 1 to 5. Aggregate Score from 0 to 100.
Time frame: 16 weeks
Fall Efficacy
16 item qestionnaire (Fall Efficacy Scale). Every answer is rated on a scale from 1 to 4.
Time frame: 16 weeks
Sleep Disturbances
7 item questionnaire (Insomnia Severity Index). Every answer is rated on a scale from 1 to 5.
Time frame: 16 weeks
Stress
10 item qestionnaire (Perceived Stress Scale). Every answer is rated on a scale from 1 to 5.
Time frame: 16 weeks
Depression
15 item questionnaire (Center for Epidemiological Studies Depression Scale). Every answer is rated on a scale from 1 to 4.
Time frame: 16 weeks
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