The goal of this pilot clinical trial is to see the potential application of a CAIX targeted PET. tracer in patients with clear cell renal cell carcinoma. The main question\[s\] it aims to answer are: * The biodistribution of the PET tracer * Whether RCC lesions can be identified by the PET tracer Participants will undergo 68Ga-NY104 PET/CT scan and images will be reviewed by nuclear medicine specialists.
PET/CT imaging of three patients using 68Ga-NY104 for medical reasons will be performed. Patients received an intravenous injection of 68Ga-NY104. Images will be obtained at 0.5 h, 1 h, and 2 h after injection. A comparative 18F-FDG PET/CT scan will also be performed if necessary. The study will be carried out on a time-of-flight PET/CT scanner. SUVmax and SUVmean of normal organs and lesions, as well as tumor-to-background ratios, will be quantitatively assessed using a region-of-interest technique.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
3
Patients will undergo PET/CT scans after receiving an intravenous injection of 68Ga-NY104
Peking Union Medical College Hospital
Beijing, Beijing Municipality, China
Biodistribution of 68Ga-NY104 in normal organs
Uptake measured by SUVmax and SUVmean in normal organs using a region-of-interest technique
Time frame: From study completion to 2 hour after completion
Tumor uptake of 68Ga-NY104
Uptake measured by SUVmax and SUVmean in suspected tumor lesions
Time frame: From study completion to 2 hour after completion
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