Endoscopic resection of superficial colorectal neoplasms decrease risk of colorectal cancer. En bloc resection is necessary for large superficial lesions with risk of superficial submucosal cancer and is advised if feasible for all lesions. Endoscopic submucosal dissection (ESD) allows en bloc resection of large superficial colorectal neoplasms, increasing curative resection rate and decreasing local recurrence risk. However, the risk of perprocedural or delayed perforation is higher compared to wild field piece meal endoscopic mucosal resection. Endoscoping clipping and closing methods mostly allow conservative treatment, but some case still necessitate surgery. The aim of our study is to describe and ananalyse outcomes after perprocedural or delayed perforation in all patients undergoing ESD and analyse the need for surgical intervention.
Study Type
OBSERVATIONAL
Enrollment
350
standard ESD performed and complicated with a perprocedural or delayed perforation
Clinique CHC
Liège, Belgium
Clinique Anjou
Angers, France
CHU Bordeaux
Bordeaux, France
CHU Dijon
Dijon, France
CHU Dupuytren
Limoges, France
Hopital Edouard Herriot
Lyon, France
Hopital Privé Jean Mermoz
Lyon, France
Nancy Hospital Center
Nancy, France
Clinique Jules Verne
Nantes, France
Hopital Europeen Georges Pompidou
Paris, France
...and 3 more locations
Surgery
Rate of surgery following perforation after ESD
Time frame: 30 days
Hospital stay
length of hospital stay (days)
Time frame: 60 days
Hospital readmission
Time frame: 30 days
Curative resection rate
Time frame: 60 days
Endoscopically closed perforation rate
Time frame: 30 days
Risk factors for endoscopic closure failure
Time frame: 30 days
30-days mortality rate
Time frame: 30 days
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