Evaluate a stannous technology for its effect on the neutrophil phenotype during an induced gingivitis state.
A 9-weeks clinical study will be conducted to evaluate a stannous fluoride dentifrice for therapeutic effects that aim to delay the onset of experimental gingivitis as well as hasten the resolution of disease.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
26
0.454% stannous fluoride toothpaste
0.76 % Sodium MonoFluorophosphate (MFP)
University of Toronto
Toronto, Ontario, Canada
Bleeding Index (BOP) and Oral Inflammatory Load
BOP is a bleeding index standard in field, oral inflammatory load as measured by neutrophil levels in oral rinses
Time frame: during patient visit over the 9 weeks
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