Asthma is the most common chronic lung disease in children. It affects more than 1 in 10 children in France. The methacholine bronchial challenge test (MBT) is indicated to assess the probability of asthma suggested by clinical symptoms by measuring the forced expiratory volume in one second (FEV1), after inhalation of a cumulative dose of methacholine. In children, the measurement of FEV1 requires a high level of cooperation from the child, which can be the source of false negatives or no result if this is not obtained. The objective of this study is to evaluate if the measurement of the respiratory function by the forced oscillations technique, allows to predict the variation of the FEV1 obtained
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
112
After each methacholine dose administred, respiratory function will be measured by forced oscillation
CHU de Montpellier
Montpellier, France
RECRUITINGChange in lung impedance measurement
Percentage change in lung impedance measurement obtained by the forced oscillation technique in relation to the dose of methacholine required to obtain bronchial hyperresponsiveness
Time frame: During the procedure
Average number of trials required for measurement of FEV1 with the spirometry technique
Average number of trials required for technically satisfactory iterative measurement of FEV1
Time frame: During the procedure
Average number of trials required for impedance measurement by forced oscillation
Average number of trials required for technically satisfactory iterative measurement of impedance
Time frame: During the procedure
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