TAVR in Adults With Pure Severe Aortic Regurgitation

Inclusion Criteria: * Age ≥ 60 years; * Patients with severe aortic regurgitation (\> grade 3) diagnosed by transthoracic echocardiography should meet any of the following conditions for semi-quantitative assessment of the degree of aortic regurgitation and any condition for quantitative assessment of the degree of aortic regurgitation: (1) semi-quantitative assessment of the degree of aortic regurgitation: aortic regurgitation bundle width/left ventricular outflow tract diameter ≥ 65%; or aortic regurgitation neck width \> 6 mm; or full-diastolic blood flow reflux in the proximal abdominal aorta; (2) quantitative assessment of the degree of aortic regurgitation: aortic regurgitation volume ≥ 60 ml/beat; or aortic regurgitation fraction ≥ 50%; or effective regurgitation orifice area ≥ 0.3 cm2 * TAVR has been performed; * Patients can understand and voluntarily participate in this clinical study, sign informed consent, and adhere to clinical follow-up. Exclusion Criteria: * History of aortic valve replacement; * Combined with moderate-severe mitral regurgitation and moderate aortic stenosis; * Acute endocarditis or other acute cardiac inflammation; * Allergic or contraindicated to related drugs (aspirin, clopidogrel, warfarin, contrast agent); * Other conditions judged by the investigator as not suitable for the study