Tumor micronecrosis is a pathological feature that reflects malignant biological behavior in hepatocellular carcinoma (HCC). This study aimed to evaluate the prognostic significance of tumor micronecrosis based on the current BCLC and TNM staging systems, and futher improve the performance of the staging models by establishing modified new staging models including tumor micronecrosis.
Study Type
OBSERVATIONAL
Enrollment
1,100
whether HCC patients have tumor micronecrosis or not
the First Affiliated Hospital, School of Medicine, Zhejiang University
Hangzhou, Zhejiang, China
the First Affiliated Hospital, School of Medicine, Zhejiang University
Hangzhou, Zhejiang, China
Overall survival
the number of months from the date of surgery to the date of the last follow-up visit or time of death.
Time frame: from date after liver resection until death or last follow-up, whichever came first, assessed up to 72 months
Disease-free survival
the number of months from the date of surgery to the date of first confirmable recurrence or death
Time frame: from date after liver resection until recurrence or last follow-up, whichever came first, assessed up to 72 months
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