Impact of a Physical Activity Intervention With Motivational Support From Peers for Prostate Cancer Patients

Objective measurement of physical activity (in MET-hr/week, Metabolic Equivalent of Task (MET), measures intensity of physical activity)

via actimetry (Actigraph GT9x, Pensacola, Florida, USA) (at 3 and 6 months).

Time frame: Inclusion, 3, 6 and 12 months

Objective measure of physical inactivity (in h/d)

via actimetry (Actigraph GT9x, Pensacola, Florida, USA)

Time frame: Inclusion, 3, 6 and 12 months

Subjective measurement of physical activity (in Metabolic equivalent of task-h/week) and sedentary time (h/d)

Via the e-Adult Physical Activity Questionnaire (e-APAQ, EA SNA-EPIS, University of Jean Monnet, Saint-Etienne, France) e-Adult Physical Activity Questionnaire (e-APAQ) assesses the 5 categories of physical activity (work, travel, daily life, leisure and sport) and daily life, leisure and sport). The minimum value is 1 and the maximum value is 300. More the physical activity score is high, more the patient is active. This questionnaire authenticates the periods of sedentarity (at work, during travel and daily life, leisure and sport). The minimum value is 1 and the maximum value is 24. More the sedentarity score is high, more the patient is sedentary.

Time frame: Inclusion, 3, 6 and 12 months

Measurement of physical capacity: walking distance (meters)

via the 6-minute walk test (6MWT).

Time frame: Inclusion, 3, 6 and 12 months

Measurement of muscle strength: biceps muscle strength (kg)

via the handgrip (JAMAR Hand Dynamometer, Nottingham, UK).

Time frame: Inclusion, 3, 6 and 12 months

Level of fatigue assessed by measuring heart rate variability (SDNN and RMSSD in ms)

via heart rate monitor connected to an actimeter (Actigraph GT3x, Pensacola, Florida, USA) for 24 hours

Time frame: Inclusion, 3, 6 and 12 months

Level of fatigue

via the FACIT-F questionnaire (Functional Assessment of Chronic Illness Therapy - Fatigue Scale). This questionnaire asseses fatigue and it impacts. The score range is 0 to 160. More the score is higher, more the fatigue is high.

Time frame: Inclusion, 3, 6 and 12 months

Health-related quality of life

via the EuroQol-5D questionnaire (EQ-5D-5L). The score range is -0.148 to 0.949. Mre the score is high, more the quality of life is good.

Time frame: Inclusion, 3, 6 and 12 months

Adoption of Acti-Pair program by physicians

Number of physicians including patients

Time frame: through end of inclusion, an average of 30 months

Adoption of Acti-Pair program by peers

Number of peers recruited

Time frame: through end of inclusion, an average of 30 months

Adoption of Acti-Pair program by Adapted Physical Activity (APA) professionals

Number of patients followed by APA professionals

Time frame: through study completion, an average of 42 Months

Time dedicated by peers, Adapted Physical Activity (APA) professionals and health professionals to the Acti-Pair program

Number of hours spend to follow-up patient specifically for the Acti-Pair program by peers, Adapted Physical Activity (APA) professionals and health professionals

Time frame: through study completion, an average of 42 Months

Assessment of the context:factors favoring and hindering implementation, achievement, adaptation and sustainability of the programme ; compliance with the programme ; social representations

Semi-structured interviews

Time frame: Before and after the implementation of the intervention

Percentage of adherence to the intervention

via the number of patients continuing the programme 12 months after initiation

Time frame: 12 months

Motivation to engage in physical activity for patients and peers

via the behavioural regulation in exercise questionnaire (BREQ-2). This questionnaire consists of 19 items includes 6 sub-scores of motivations : introjected regulation (3 items), external regulation (4 items), intrinsic regulation (4 items), integrated regulation, amotivation (4 items) and identified regulation (4 items) on a scale from 1 (Not at all true for me) to 5 (Absolutely true for me).

Time frame: Inclusion, 3, 6 and 12 months

Alliance between the patient and the peer

via the Working Alliance Inventory - short version (WAI-SR). This questionnaire measures three dimensions: bonding (development of a positive interpersonal attachment between the patient and the peer including mutual trust and respect), tasks (each partner's perception of the appropriateness and effectiveness of the care tasks, as well as tasks, as well as shared responsibility for their execution) and goals (understanding, validation and acceptance by both partners of the objectives of change in physical activity management). Patients rate items on a 5-point Likert scale anchored at each end with 'rarely or never' (1) and 'always' (5). The Goal, Task and Bond domains each have scores ranging from 5 to 20. Higher scores indicate a better therapeutic alliance.

Time frame: 12 months

Patients, peers and professionals satisfaction

Via a satisfaction questionnaire constructed for the Acti-Pair programme. The proposed responses are a likert scale ranging from Strongly Agree to Strongly Disagree. Each item will be described with a percentage of Likert scale for each response. More participants will fill out they have been strongly agree, more they will be satisfied.This questionnaire does not have a score.

Time frame: 12 months

Cost per quality adjusted life year (QALY) gained through the intervention (quality adjusted life year)

Quality of life data will be collected (e.g. quality of life using the EQ-5D-5L questionnaire, Appendix 3), transformed into utilities to calculate quality adjusted life year (QALY), and the number of patients continuing physical activity at 12 months. Cost data will be collected throughout the study, in each of the 8 departments involved. The analysis will be carried out from the payer's (health insurance) perspective. The time horizon will be that of the study (12 months), and therefore in accordance with French guidelines (HAS), no discount rate will be applied

Time frame: 12 months

Cost per patient continuing physical activity at 12 months through the intervention

The costs will include : - direct medical costs : health professionals consultations, peer-to-peer, patient sessions with APA professionals - indirect costs of implementing the intervention: training, facility rental operating costs, investment in small equipment

Time frame: 12 months