Safety of CRIS100 on Treatment Spinal Cord Injury

Inclusion Criteria: * Signature of the Free and Informed Consent Term by the participant or legal guardian * Age between 18 and 70 years old; * Thoracic spinal cord injury between T2 and T10, with surgical indication, occurred less than 72 hours before surgery; * Presence of bulbo cavernosum reflex; * Patients with a lesion classified as ASIA A according to the ISNCSCI (2019 revision); Exclusion Criteria: * Absence of bulbocavernous reflex up to 72 hours after the trauma. * Presence of severe brain trauma. * Patients with lesions above T2 or below T10. * More than one site of spinal cord injury. * History of alcohol or illicit drug abuse, as defined by DSM 5 (Diagnostic and Statistical Manual of Mental Disorders, 5th Edition or later). * Patients who need permanent mechanical respiratory support. * Polytraumatized patients who, in the investigator's assessment, compromise the neurological evolution. * Neurological diseases or functional dependence of any etiology prior to the trauma. * Any other comorbidity that, at the discretion of the investigator, makes it impossible to include the patient in the study.