The main purpose of this study is to identify important treatment attributes for post-radical cystectomy (RC) treatment for participants with MIBC (Muscle-Invasive Bladder Cancer) and assess the relative importance of treatment attributes for post-RC treatment in Japan.
Study Type
OBSERVATIONAL
Enrollment
115
Local Institution - 0001
Morrisville, North Carolina, United States
Overall survival
Median overall survival (years)
Time frame: Up to 1 year after radical cystectomy
5-year survival rate
Defined as the percentage of patients that are alive after 5 years
Time frame: Up to 1 year after radical cystectomy
Disease-free survival (DFS)
Median disease-free survival (year)
Time frame: Up to 1 year after radical cystectomy
Probability of side effect-related treatment discontinuation
Defined as the percent likelihood that a patient will stop treatment due to a side effect
Time frame: Up to 1 year after radical cystectomy
Number of participants who experience treatment side effects
Defined as the percentage of participants who experience nausea, diarrhea, fatigue, skin-related side effects (e.g. pruritus, rash), endocrine system-related side effects (e.g. hypothyroidism), anemia, alopecia, reduced renal function, cardiac impairment, leukopenia, neutropenia, and thrombocytopenia due to treatment
Time frame: Up to 1 year after radical cystectomy
Overall severity of side effects
Defined as the severity of side effects categorized as "None", "mild-to-moderate", or "severe"
Time frame: Up to 1 year after radical cystectomy
Treatment Convenience
Defined as the route of administration and frequency of administration per day or week (Infusions once every week, 2 weeks, or 4 weeks)
Time frame: Up to 1 year after radical cystectomy
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Treatment duration
Defined as the total duration for continuous administration of treatment categorized as 2 months, 4 months, or 1 year
Time frame: Up to 1 year after radical cystectomy
Hospitalization
Defined as the length of hospitalization required for administration of treatment categorized as 0 days (no hospitalization required for administration of treatment), 1 week, or more than 1 week
Time frame: Up to 1 year after radical cystectomy
Frequency of outpatient consultations
Defined as the number of outpatient consultations required for treatment administration and monitoring categorized as every 2 weeks, 4 weeks, or 3 months
Time frame: Up to 1 year after radical cystectomy
Annual treatment costs
Defined as the annual out-of-pocket treatment costs, categorized as 10,000, 300,000, or 650,000 JPY
Time frame: Up to 1 year after radical cystectomy