The purpose of this study is to investigate the cerebral activation during visual motor simulation in healthy subjects in 3 conditions: observation (OBS), observation and imagination (OBS-IM) and observation and realization (OBS-REAL). The investigators goal is to compare cerebral activation during the three different tasks using EEG and fNIRS.
Mirror therapy is a rehabilitation technique that has been shown to be effective in restoring upper limb motor skills in patients with stroke. However, it comes up against certain constraints of clinical use such as installation difficulties or the obligation of symmetrical bilateral work. These constraints can be limited by the use of so-called 2nd generation virtual mirror therapy technologies. It is therefore likely that these new technologies will improve the feasibility and effectiveness of mirror therapy in rehabilitation. The brain mechanisms involved in virtual mirror therapy are not yet fully understood. EEG (Electroencephalography) and fNIRS (functional Near Infra Red Spectroscopy) are two functional method that allows to study the cerebral cortex changes during different tasks (like fMRI). These techniques therefore makes it possible to study brain activation under more ecological conditions than fMRI and are therefore particularly suitable for exploring rehabilitation techniques. This research aims to study and compare in healthy subjects, using EEG and fNIRS, the brain regions involved in three tasks using a virtual mirror therapy device (IVS4 apparatus ; Dessintey, France) implying lower limb control. The protocol has 3 conditions : observation (OBS), observation and imagination (OBS-IM) and observation and realization (OBS-REAL). The order of the 3 conditions will then be randomized to avoid potential biases linked to the sequence of conditions. The EEG recording will used the 32 channels ENOBIO apparatus. The fNIRS will used the Brite MKII apparatus
Study Type
OBSERVATIONAL
Enrollment
38
Subject is seated in a chair facing IVS4. He places his right lower under the screen. The flexion / extension movement of the ankle at a frequency of 0.5 Hz is then recorded. Then for the "mirror" effect the software reverses the recorded movement, the lower right limb becomes the lower left limb on the screen. The subject only observe the movement on the screen during the recordings. The subject does not produce any movement.
Subject is seated in a chair facing IVS4. He places his right lower under the screen. The flexion / extension movement of the ankle at a frequency of 0.5 Hz is then recorded. Then for the "mirror" effect the software reverses the recorded movement, the lower right limb becomes the lower left limb on the screen. The subject observe the movement but also imagine to realized it.
CHU de Saint-Etienne
Saint-Etienne, France
Change in the EEG spectral alpha and beta-band power (8-12 and 12-30Hz) during movement (Event related Desynchronisation)
Beta desynchronization in dB normalized to a baseline before the movement.
Time frame: Day 0
Change in the beta band after movement (Beta-Rebound).
Beta Rebound power in dB normalized to a baseline before the movement.
Time frame: Day 0
Mean change in the concentration of oxyhemoglobin during the task
Changes in the concentration of oxyhemoglobin during the task measured with Fnirs device
Time frame: Day 0
Mean change in the concentration of deoxyhemoglobin during the task
Changes in the concentration of deoxyhemoglobin during the task measured with Fnirs device
Time frame: Day 0
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Subject is seated in a chair facing IVS4. He places his right lower under the screen. The flexion / extension movement of the ankle at a frequency of 0.5 Hz is then recorded. Then for the "mirror" effect the software reverses the recorded movement, the lower right limb becomes the lower left limb on the screen. The subject observe the movement on the screen and realized it