In this study, investigators aimed to develop and validate a risk score to predict severe outcomes (e.g., mortality and ICU admission) in children who were admitted to the Children's Hospital of Fudan University between 2017 and 2022 due to community-acquired pneumonia (CAP). The objectives were as follows. 1. Develop a risk prediction model based on demographic, comorbidity, clinical characteristics, laboratory data, and chest radiographic reports to predict severe outcomes among children hospitalized with CAP; 2. Develop a risk scoring system and determine the cut-off point; 3. Externally validate the easy-to-use risk score.
Study Type
OBSERVATIONAL
Enrollment
6,000
epidemiological data (e.g., age, sex, and residential area), clinical characteristics (e.g., fever, cough, and wheeze), laboratory data (e.g., white blood cell, c-reaction protein, and procalcitonin), and chest radiographic reports (e.g., X-ray, CT, and ultrasound)
Children's Hospital of Fudan University
Shanghai, Shanghai Municipality, China
in-hospital mortality
in-hospital mortality among children hospitalized with CAP
Time frame: from admission to discharge, an average of 7 days
admission to ICU
admission to a intensive care unit for over 24 hours
Time frame: from admission to discharge, an average of 7 days
septic shock
occurrence of septic shock during admission
Time frame: from admission to discharge, an average of 7 days
treatment for severe pneumonia
vasoactive agents, positive-pressure ventilation or chest drainage, or extracorporeal membrane oxygenation
Time frame: from admission to discharge, an average of 7 days
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.